1233 74 16970 2 59591 document 16970 Data.zip application/zip 26f8f901a4bf0d73ed09985b9684a94f MD5 50063668 2023-03-29 09:11:32 https://researchdata.bath.ac.uk/1233/1/Data.zip 1233 1 1 application/zip other en public cc_by

Data.zip

data archive 11301 disk0/00/00/12/33 2023-04-28 09:45:01 2024-07-18 12:32:06 2023-04-28 09:45:01 data_collection show Turner Joe jt2156@bath.ac.uk 0000-0002-9476-6917 University of Bath FALSE Lay Emily el605@bath.ac.uk University of Bath FALSE Jungwirth Ute U.Jungwirth@bath.ac.uk 0000-0002-4673-3096 University of Bath FALSE Varenko Valentyna V.Varenko@bath.ac.uk University of Bath FALSE Gill Richie R.Gill@bath.ac.uk 0000-0002-7740-2062 University of Bath FALSE Estrela Pedro P.Estrela@bath.ac.uk 0000-0001-6956-1146 University of Bath FALSE Leese Hannah H.S.Leese@bath.ac.uk 0000-0003-4523-3804 University of Bath TRUE DataCollector Turner Joe jt2156@bath.ac.uk 0000-0002-9476-6917 University of Bath DataCollector Lay Emily el605@bath.ac.uk University of Bath DataCollector Jungwirth Ute U.Jungwirth@bath.ac.uk 0000-0002-4673-3096 University of Bath DataCollector Varenko Valentyna V.Varenko@bath.ac.uk University of Bath DataCollector Gill Richie R.Gill@bath.ac.uk 0000-0002-7740-2062 University of Bath Supervisor Estrela Pedro P.Estrela@bath.ac.uk 0000-0001-6956-1146 University of Bath Supervisor Leese Hannah H.S.Leese@bath.ac.uk 0000-0003-4523-3804 University of Bath DK0020 FV0010 GE0010 GS0010 GS0070 dept_chem_eng dept_elec_eng dept_mech_eng dept_pharm This dataset pertains to a study involving the use of 3D printed hollow microneedles (HMNs) for the detection of c-reactive protein and procalcitonin. It includes: - Chemical modification of the HMNs surface to enhance its ability to uptake fluids rapidly; - the mechanical properties and skin penetration of both HMNs; - Characterizations' of the material, including FTIR, TGA and AFM; - Cytotoxicity assessment of the HMNs; - Uptake of CRP and PCT in solutions and detection using LFTs. The data provides a suggestion towards the use of HMNs for the effective rapid diagnostics of inflammation markers. 2023-04-28 University of Bath public RightsHolder University of Bath Engineering and Physical Sciences Research Council https://doi.org/10.13039/501100000266 EP/V010859/1 Minimally Invasive Molecularly Imprinted Conductive Nanoneedle Sensors Royal Society https://doi.org/10.13039/501100000288 RGS\R1\201185 Molecularly Imprinted Conductive Microneedles Abbott Diabetes Care https://doi.org/10.13039/100011946 2283996 Studentship - Detect, treat and tell: Skin patches to sense infection and indicate recovery cent_c3bio Cytotoxicity: HMNs and 3D printed parts were tested against human dermal fibroblast cells and breast tumour cells. Samples were exposed to the cells and cell death was recorded over 24 hours. Alternatively, cell growth was recorded over 48 hours. CRP and PCT detection: A spiked solution of relevant concentration was prepared. LFTs were placed within the HMNs. HMNs were placed within PBS. Mechanical properties: HMNs were tested on a DMA up to 10 newtons. Data is proved in the form of excel document. Skin Penetration: HMNs were placed on porcine skin and a known force was applied and the resultant skin pores were optically imaged. Data is in the form of images. Wettability: Square samples were printed and treated with various treatments. The contact angle was taken over time to determine the effect. Raw data and data analysis can been found in the respective files. The data is provided in MS Excel format. en 1 10.15125/BATH-01233 https://doi.org/10.1002/admt.202300259 pub open Dataset