The dataset has been created through airflow building simulation using EnergyPlus AirflowNetwork (AFN) and Contam. The case study is represented by a single-room shelter located in Hitsats (Ethiopia). Five ventilation layouts: single-side ventilation wind-driven, cross-ventilation wind-driven, single-side ventilation buoyancy-driven, single-side two windows buoyancy-driven, and cross-ventilation buoyancy-driven.