Data collection methods are described in full in the publication "Influence of Block Microstructure on the Interaction of Styrene-Maleic Acid Copolymer Aggregates and Lipid Nanodiscs". Briefly, various copolymers between styrene and maleic anhydride were prepared by RAFT polymerisation, which, when using DDMAT, results in a relatively-large and hydrophobic SC12 end group (SMAnh-SC12). This block sequence was then inverted by first synthesising a poly(sty) macro-RAFT agent, from which a Sty:MA alternating block may be polymerised. A commercial variant, SMA2000, synthesised by free-radical polymerisation was also used for comparison. All copolymers were then hydrolysed to the acid form (SMA) before workup and purification.