This is the data set related to the paper of the same title. In this investigation a novel synergistic approach for the bioremediation of metal-contaminated water and bioenergy production was developed. Two microalgae, Chlorella vulgaris and Arthrospira platensis (Spirulina), and two macroalgae, Ulva lactuca and Sargassum muticum, were used as passive bioremediation agents for the metals Ni(II), Zn(II), Cd(II) and Cu(II). The metals were added singularly and in combination. The metal contaminated biomass was then processed through hydrothermal liquefaction to yield four phases: a bio-crude oil, an aqueous phase, solid residue and gas. Within this data set is the raw data for metal absorption and for the metal distribution in the various phases of the reaction