Folders: Figure_1 : .tiff files for respresentative blots seen in Figure 1. Figure_2 : .tiff files for respresentative blots seen in Figure 2. Figure_3 : .tiff files for respresentative blots seen in Figure 3. Figure_4 : .tiff files for respresentative blots seen in Figure 4. Figure_S2 : .tiff files for respresentative blots seen in Supplementary Figure 2. Figure_S4 : .tiff files for respresentative blots seen in Supplementary Figure 4. .tiff files are not required for Supplementary Figure S3, as these are overexposed images from the original .tiff files from Figure 2. All_blots_for_quantification: .tiff files for each experiment used for densitometry quantification for paper; Numbers correspond to experiment number, seen in Excel document "collated_InsR_values_for_archive.xlsx" Annotated blots are found in PowerPoint of corresponding experiment/Figure folder. blots used for quantification are listed in Excel spreadsheet, "Experiments_used_for_each_graph.xlsx".