Dataset for Optical Manipulation of Whispering Gallery Mode Microlasers for Controlled Cellular Delivery

The dataset documents experiments examining the interaction between whispering gallery mode (WGM) microlasers and non-phagocytic mammalian cells, with particular emphasis on controlled delivery using optical trapping and real-time observation of the cellular uptake process.

It includes time-resolved spectral data acquired from individual microlasers during their interaction with cells. In some cases, these spectra have been analysed using Voigt function fitting to quantify features such as linewidth broadening and mode splitting, which are indicative of changes in the local optical environment.

The dataset also contains high-resolution microscopy imaging data corresponding to the experiments. These images provide visual context for the spectral measurements, showing microlaser positioning, contact with the cell membrane, and stages of internalization.

In addition, the dataset provides derived data obtained through fitting the spectral measurements to an optical model described in the associated work. This analysis yields estimates of the external refractive index surrounding the microlasers.

Keywords:
Whispering gallery mode, microlasers, optical trapping, cellular delivery, biosensing, Intracellular microlasers, biointegrated photonics.

Cite this dataset as:
Caixeiro, S., Rodríguez-Sevilla, P., Dholakia, K., Gather, M., 2026. Dataset for Optical Manipulation of Whispering Gallery Mode Microlasers for Controlled Cellular Delivery. Bath: University of Bath Research Data Archive. Available from: https://doi.org/10.15125/BATH-01674.

Export

Data

data.zip
application/zip (55MB)
Creative Commons: Attribution 4.0

Creators

Paloma Rodríguez-Sevilla
Autonomous University of Madrid

Kishan Dholakia
University of St Andrews

Malte C. Gather
University of St Andrews; University of Cologne

Contributors

University of Bath
Rights Holder

Documentation

Data collection method:

Details are available in the associated publication

Additional information:

The data is organised in subfolders related to the figure in the publication.

Funders

Engineering and Physical Sciences Research Council
https://doi.org/10.13039/501100000266

Resonant and shaped photonics for understanding the physical and biomedical world
EP/P030017/1

Alexander von Humboldt Foundation
https://doi.org/10.13039/100005156

Alexander von Humboldt Professorship to M.C.G

Spanish State Research Agency
https://doi.org/10.13039/003x0zc53

Juan de la Cierva Postdoctoral Fellowship
IJC2019-041915

Autonomous University of Madrid
https://doi.org/10.13039/01cby8j38

Santander Movilidad de Jóvenes Investigadores Scholarship

Australian Research Council
https://doi.org/10.13039/501100000923

Levitated Quantum Optomechanics with Trapped, Rotating Microparticles
DP220102303

Australian Research Council
https://doi.org/10.13039/501100000923

The Intelligent Microscope – novel optical imaging at depth
FL210100099

Publication details

Publication date: 7 July 2026
by: University of Bath

Version: 1

DOI: https://doi.org/10.15125/BATH-01674

URL for this record: https://researchdata.bath.ac.uk/1674

Related papers and books

Caixeiro, S., Rodríguez‐Sevilla, P., Dholakia, K., and Gather, M. C., 2026. Optical Manipulation of Whispering Gallery Mode Microlasers for Controlled Cellular Delivery. Advanced Optical Materials. Available from: https://doi.org/10.1002/adom.71421.

Contact information

Please contact the Research Data Service in the first instance for all matters concerning this item.

Contact person: Soraya Caixeiro

Departments:

Faculty of Science
Physics

Research Centres & Institutes
Centre for Photonics and Photonic Materials