Single molecule experimental data for unphosphorylated Aurora-A measurements in Gilburt et al, Chemical Science 2019
Raw and partially processed data for the dwell time histogram in the following publication: James A H Gilburt, Paul Girvan, Julian Blagg, Liming Ying, Charlotte A Dodson (2019) Ligand discrimination between active and inactive activation loop conformations of Aurora-A kinase is unmodified by phosphorylation. Chemical Science.
Cite this dataset as:
Dodson, C.,
Gilburt, J.,
Ying, L.,
2019.
Single molecule experimental data for unphosphorylated Aurora-A measurements in Gilburt et al, Chemical Science 2019.
Zenodo.
Available from: https://doi.org/10.5281/zenodo.2555379.
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Creators
Charlotte Dodson
University of Bath
James Gilburt
Imperial College London
Liming Ying
Imperial College London
Contributors
University of Bath
Rights Holder
Funders
Imperial College London
https://doi.org/10.13039/501100000761
Imperial College Junior Research Fellowship – Using single molecule spectroscopy to inform drug discovery in protein kinases
Biotechnology and Biological Sciences Research Council (BBSRC)
https://doi.org/10.13039/501100000268
Conformational selection in Aurora-A kinase: competition between activator- and inhibitor- promoted forms
BB/M021149/1
Wellcome Trust
https://doi.org/10.13039/100010269
Value in People Award
Imperial College London
https://doi.org/10.13039/501100000761
AstraZeneca Innovation Fund grant
Publication details
Publication date: 7 March 2019
by: Zenodo
Version: 1
DOI: https://doi.org/10.5281/zenodo.2555379
URL for this record: https://researchdata.bath.ac.uk/id/eprint/617
Related papers and books
Gilburt, J. A. H., Girvan, P., Blagg, J., Ying, L., and Dodson, C. A., 2019. Ligand discrimination between active and inactive activation loop conformations of Aurora-A kinase is unmodified by phosphorylation. Chemical Science, 10(14), 4069-4076. Available from: https://doi.org/10.1039/c8sc03669a.
Contact information
Please contact the Research Data Service in the first instance for all matters concerning this item.
Contact person: Charlotte Dodson
Life Sciences
Pharmacy & Pharmacology
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Centre for Therapeutic Innovation
