Dataset for "Tri-mode optical biopsy probe with fluorescence endomicroscopy, Raman spectroscopy, and time resolved fluorescence spectroscopy"

Data supporting "Tri-mode optical biopsy probe with fluorescence endomicroscopy, Raman spectroscopy, and time resolved fluorescence spectroscopy", including figures from the article, supplementary figures and diagrams of the experimental setups used, bend loss data from the fibre used for Time Resolved Fluorescence Spectroscopy (TRFS), and the raw Optical EndoMicroscopy (OEM) video files used to produce figure 5.

This body of work characterises the performance of an optical fibre probe that was designed and built to provide three complimentary optical methods of endoscopically interrogating human tissue: Optical EndoMicroscopy (OEM), Time Resolved Fluorescence Spectroscopy (TRFS), and Raman spectroscopy. Its ability to characterise standard targets was evaluated, both when subjected to a sequence of bends, and then within a model of a human lung. Ex-vivo human lung tissue was also used as a target to explore its tissue characterisation capabilities. These data sets form part of the pre-clinical testing and validation required for progression to its intended application in pulmonology.

Keywords:

endoscopy microendoscopy raman endoscopy fluorescence endomicroscopy time-resolved fluorescence spectroscopy optical biopsy

Subjects:

Medical and health interface

Optics, photonics and lasers

Tools, technologies and methods

Cite this dataset as:
Wood, H., Ehrlich, K., Yerolatsitis, S., Kufcsák, A., Stone, J., Quinn, T., Fernandes, S., 2022. Dataset for "Tri-mode optical biopsy probe with fluorescence endomicroscopy, Raman spectroscopy, and time resolved fluorescence spectroscopy". Bath: University of Bath Research Data Archive. Available from: https://doi.org/10.15125/BATH-01174.

Export

Data

TriModeOpticalBiopsyPaperData.zip
application/zip (31MB)
Creative Commons: Attribution 4.0

Creators

Harry Wood
University of Bath

0000-0003-4430-2257

Katjana Ehrlich
Heriot-Watt University; University of Edinburgh

0000-0002-8387-9641

Stephanos Yerolatsitis
University of Central Florida

0000-0002-6268-3674

András Kufcsák
University of Edinburgh

0000-0002-3242-1737

James Stone
University of Bath

0000-0002-3420-9860

Tom Quinn
University of Edinburgh

0000-0003-3544-4333

Susan Fernandes
University of Edinburgh

0000-0001-5966-4010

Contributors

Dominic Norberg
Contributor
University of Edinburgh

Nia Caitlin Jenkins
Contributor
University of Edinburgh

0000-0002-4330-4544

Vikki Young
Contributor
University of Edinburgh

Irene Young
Contributor
University of Edinburgh

Katie Hamilton
Contributor
University of Edinburgh

Sohan Seth
Contributor
University of Edinburgh

0000-0002-7464-4752

Ahsan R. Akram
Contributor
University of Edinburgh

0000-0003-4605-1682

Robert R. Thomson
Contributor
Heriot-Watt University; University of Edinburgh

0000-0003-4978-1488

Keith Finlayson
Contributor
University of Edinburgh

Kevin Dhaliwal
Project Manager
University of Edinburgh

0000-0002-3925-3174

University of Bath
Rights Holder

University of Edinburgh
Rights Holder

Documentation

Data collection method:

Full details of the methodology can be found in the associated paper.

Methodology link:

Wood, H. A. C., Ehrlich, K., Yerolatsitis, S., Kufcsák, A., Quinn, T. M., Fernandes, S., Norberg, D., Jenkins, N. C., Young, V., Young, I., Hamilton, K., Seth, S., Akram, A., Thomson, R. R., Finlayson, K., Dhaliwal, K., and Stone, J. M., 2022. Tri‐mode optical biopsy probe with fluorescence endomicroscopy, Raman spectroscopy, and time‐resolved fluorescence spectroscopy. Journal of Biophotonics, 16(2). Available from: https://doi.org/10.1002/jbio.202200141.