Dataset for "Conductive polymer-coated 3D printed microneedles: biocompatible platforms for minimally invasive biosensing interfaces"

This dataset includes all the data presented and analyzed in the aforementioned paper, "Conductive polymer-coated 3D printed microneedles: biocompatible platforms for minimally invasive biosensing interfaces". These include: CAD designs, SEM and AFM micrographs, FTIR, Raman, and EDS spectra, water sessile drop images, DMA compression tests, ex vivo skin penetration bright-field microscopy images, cyclic voltammograms, four-point probe resistivity measurements, battery-LED system photographs, and cytotoxicity assay measurements.

Subjects:

Cite this dataset as:
Keirouz, T., Mustafa, Y., Turner, J., Lay, E., Jungwirth, U., Marken, F., Leese, H., 2023. Dataset for "Conductive polymer-coated 3D printed microneedles: biocompatible platforms for minimally invasive biosensing interfaces". Bath: University of Bath Research Data Archive. Available from: https://doi.org/10.15125/BATH-01210.

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Data

FTIR.zip
application/zip (11MB)
Creative Commons: Attribution 4.0

Fourier-transform infrared spectroscopy analysis

Raman.zip
application/zip (8MB)
Creative Commons: Attribution 4.0

Raman spectroscopy analysis

EDS.zip
application/zip (10MB)
Creative Commons: Attribution 4.0

Energy-dispersive X-ray spectroscopy (EDS) analysis

SEM.zip
application/zip (233MB)
Creative Commons: Attribution 4.0

Scanning electron microscopy (SEM) imaging micrographs

AFM.zip
application/zip (25MB)
Creative Commons: Attribution 4.0

Atomic force microscopy (AFM) imaging

Four-point probe and CV.zip
application/zip (259kB)
Creative Commons: Attribution 4.0

Four-point probe resistivity measurements and cyclic voltammetry

WCA.zip
application/zip (2MB)
Creative Commons: Attribution 4.0

Sessile drop measurements, water contact angle (WCA)

Battery-led system.zip
application/zip (360MB)
Creative Commons: Attribution 4.0

Battery-LED system photographs and videos

MN ex vivo … penetration.zip
application/zip (7MB)
Creative Commons: Attribution 4.0

Microneedle ex vivo skin penetration bright-field microscopy images.

DMA compression testing.zip
application/zip (5MB)
Creative Commons: Attribution 4.0

Dynamic mechanical analysis (DMA) compression testing analysis

Cytotoxicity.zip
application/zip (20kB)
Creative Commons: Attribution 4.0

Cytotoxicity assay (cell viability) measurements

Mixed access regime: The MN CAD design file (CAD design.zip) can be accessed by bone fide researchers only.

Creators

Tony Keirouz
Data Collector
University of Bath

Yasemin Mustafa
Data Collector
University of Bath

Joe Turner
Data Collector
University of Bath

Emily Lay
Data Collector
University of Bath

Ute Jungwirth
Project Member
University of Bath

Frank Marken
Project Member
University of Bath

Hannah Leese
Project Leader
University of Bath

Contributors

University of Bath
Rights Holder

Documentation

Data collection method:

The methodology can be found in the associated paper.

Technical details and requirements:

Equipment: 1. Formlabs form 3, FormWash and FormCure (FormLabs, USA); 2. Zepto Model 2 Diener Plasma Reactor (Diener Electronics, Germany); 3. iD7 attenuated total reflectance (ATR)-mode of a Nicolet™ iS5 FTIR spectrometer (Thermo Fisher Scientific, USA); 4. inVia™ confocal Raman microscope (Renishaw, UK); 5. Contact angle measurement system, OCA 25 (Data Physics, UK); 6. SU3900 scanning electron microscopy (SEM) instrument (Hitachi, Japan); 7. Jupiter XR (Oxford Instruments) atomic force microscope (AFM) was used in blueDrive™ Tapping Mode with AC160TS-R3 tips; 8. 10X-200X USB digital microscope with a 0.3-megapixel resolution (United Scope, Netherlands); 9. Jandel RM3000 (Jandel Engineering, UK); 10. µAutolab type II potentiostat/galvanostat (Metrohm, Switzerland); 11. Mettler Toledo DMA1 (Mettler Toledo, USA) dynamic mechanical analyser (DMA); 12. BMG FLUOstar Omega (BMG Labtech, UK) plate reader. Software: 1. Excel and PowerPoint (v. 2016, Microsoft, USA); 2. Origin (v. 2022b, Electronic Arts); 3. Fiji-ImageJ, contact angle add-on, v.1.52 (National Institutes of Health, USA) 4. Spectragryph (v. 1.2, effemm2.de); 5. Nova (v. 2.1, Metrohm, Switzerland); 6. AZtec software package (Oxford Instruments, UK); 7. AutoCAD (Autodesk, USA); 8. Prism (v.9, GraphPad Software, USA).

Methodology link:

Keirouz, A., Mustafa, Y. L., Turner, J. G., Lay, E., Jungwirth, U., Marken, F., and Leese, H. S., 2023. Conductive Polymer‐Coated 3D Printed Microneedles: Biocompatible Platforms for Minimally Invasive Biosensing Interfaces. Small, 19(14), 2206301. Available from: https://doi.org/10.1002/smll.202206301.

Funders

Engineering and Physical Sciences Research Council
https://doi.org/10.13039/501100000266

Minimally Invasive Molecularly Imprinted Conductive Nanoneedle Sensors
EP/V010859/1

Molecularly Imprinted Conductive Microneedles
RGS\R1\201185

Publication details

Publication date: 3 January 2023
by: University of Bath

Version: 1

DOI: https://doi.org/10.15125/BATH-01210

URL for this record: https://researchdata.bath.ac.uk/id/eprint/1210

Related papers and books

Keirouz, A., Mustafa, Y. L., Turner, J. G., Lay, E., Jungwirth, U., Marken, F., and Leese, H. S., 2023. Conductive Polymer‐Coated 3D Printed Microneedles: Biocompatible Platforms for Minimally Invasive Biosensing Interfaces. Small, 19(14), 2206301. Available from: https://doi.org/10.1002/smll.202206301.

Contact information

Please contact the Research Data Service in the first instance for all matters concerning this item.

Contact person: Hannah Leese

Departments:

Faculty of Engineering & Design
Chemical Engineering

Research Centres & Institutes
Centre for Biosensors, Bioelectronics and Biodevices (C3Bio)