Dataset for Petratou, Spencer, Kelsh and Lister 'The MITF paralog tfec is required in neural crest development for fate specification of the iridophore lineage from a multipotent pigment cell progenitor'

The data consist of (1) iridophore counts in WT or tfec mutant embryos at 3 dpf (Fig. 3F); (2) iridophore counts from tfec mutants injected with tfec cDNA construct or uninjected controls (Fig. 3K); (3) iridophore counts from WT embryos injected with various control and tfec-expression plasmids, and uninjected controls (Fig. 3M); (4) melanocyte counts in tfec mutants compared to WT siblings at 30 hpf and 4 dpf (Fig. 4I,L).

Keywords:
iridophore, melanophore, zebrafish, pigment cell, tfec, gene regulatory network
Subjects:

Cite this dataset as:
Petratou, K., Lister, J., Kelsh, R., 2021. Dataset for Petratou, Spencer, Kelsh and Lister 'The MITF paralog tfec is required in neural crest development for fate specification of the iridophore lineage from a multipotent pigment cell progenitor'. Bath: University of Bath Research Data Archive. Available from: https://doi.org/10.15125/BATH-00743.

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Data

SupplFig3 raw data KP.xlsx
application/vnd.openxmlformats-officedocument.spreadsheetml.sheet (9kB)
Creative Commons: Attribution 4.0

Original counts data for Supp. Fig. 3

Fig. 3Fdata.xlsx
application/vnd.openxmlformats-officedocument.spreadsheetml.sheet (10kB)
Creative Commons: Attribution 4.0

Original counts for Fig. 3F

Figure 3K data.xlsx
application/vnd.openxmlformats-officedocument.spreadsheetml.sheet (14kB)
Creative Commons: Attribution 4.0

Original embryo counts for Fig. 3K

Fig3M_tfecOE_raw.xlsx
application/vnd.openxmlformats-officedocument.spreadsheetml.sheet (10kB)
Creative Commons: Attribution 4.0

Original iridophore counts for Fig. 3M

Fig. 4data.xlsx
application/vnd.openxmlformats-officedocument.spreadsheetml.sheet (18kB)
Creative Commons: Attribution 4.0

Original counts for Fig. 4I,L

Creators

Kleio Petratou
University of Bath

James A Lister
Virginia Commonwealth University

Robert Kelsh
University of Bath

Contributors

University of Bath
Rights Holder

Documentation

Data collection method:

Full details of the methodology may be found in the associated paper.

Methodology link:

Petratou, K., Spencer, S. A., Kelsh, R. N., and Lister, J. A., 2019. TheMITFparalogtfecis required in neural crest development for fate specification of the iridophore lineage from a multipotent pigment cell progenitor. bioRxiv. Available from: https://doi.org/10.1101/862011.

Funders

Biotechnology and Biological Sciences Research Council
https://doi.org/10.13039/501100000268

A Systems Biology Approach to Neural Crest Development
BB/L00769X/1

PhD studentship (Petratou)

National Center for Advancing Translational Sciences
https://doi.org/10.13039/100006108

Clinical and Translational Science Award
UL1TR000058

Virginia Commonwealth University
https://doi.org/10.13039/100009238

AD Williams Scholarship (Lister)

Publication details

Publication date: 5 January 2021
by: University of Bath

Version: 1

DOI: https://doi.org/10.15125/BATH-00743

URL for this record: https://researchdata.bath.ac.uk/id/eprint/743

Related papers and books

Petratou, K., Spencer, S. A., Kelsh, R. N., and Lister, J. A., 2021. The MITF paralog tfec is required in neural crest development for fate specification of the iridophore lineage from a multipotent pigment cell progenitor. PLOS ONE, 16(1), e0244794. Available from: https://doi.org/10.1371/journal.pone.0244794.

Contact information

Please contact the Research Data Service in the first instance for all matters concerning this item.

Contact person: Robert Kelsh

Departments:

Life Sciences
Biology & Biochemistry

Research Centres & Institutes
Centre for Regenerative Medicine