Datset for "Resting skeletal muscle ATGL and CPT1B are associated with peak fat oxidation rates in men and women but do not explain observed sex differences"

The aim of this study was to examine the relationship between the content of key proteins involved in adipose tissue and skeletal muscle fat metabolism with PFO. This study was a cross-sectional study that recruited n = 115 adults (aged 18 – 65 years) who had varying levels of cardiorespiratory fitness, habitual physical activity levels and body composition. From this recruited sample, n = 36 participants opted to have adipose tissue and/or skeletal muscle biopsies. Thus, this study reports data on this sub-set of participants.

The dataset includes demographic data of the participants who opted for adipose tissue and/or skeletal muscle biopsies (n=36) recruited as part of a larger study (n=115). Additionally, data from the three trials they participated in are included. The types of data that were collected during the trials are as follows - Trial A and Trial B followed identical protocols that involved anthropometric measurements, resting metabolic rate, a resting venous blood sample (to look at various plasma metabolite and hormone concentrations) and the completion of a graded exercise test to determine PFO and FATMAX by indirect calorimetry. At Trial C, body composition was assessed (via a dual energy x-ray absorptiometry scan) and optional adipose tissue and/or skeletal muscle biopsies were obtained. The adipose tissue and muscle biopsy data revolves around the content of several key proteins involved in fat metabolism in adipose tissue and skeletal muscle that may regulated fat use during exercise. All trials were completed in an overnight fasted-state.