Dataset for "A randomized controlled trial to isolate the effects of fasting and energy restriction on weight loss and metabolic health in lean adults"

This dataset contains the archived data pertaining to the article "A randomized controlled trial to isolate the effects of fasting and energy restriction on weight loss and metabolic health in lean adults". The associated trial is registered and available to view at ClinicalTrials.gov (ref: NCT02498002).

All blood parameters reported in this dataset relate to venous samples drawn during the preliminary visit (Baseline), in a ~10 hour overnight fasted state (Pre and Post) and at regular intervals following a standardised breakfast and lunch both before and after the intervention. Both intra- and inter-assay/plate coefficients of variation are reported for each parameter. The dataset also contains measurements of participants' food intake, energy expenditure, and relative gene expressions.

Keywords:
Fasting, Energy intake, Appetite hormones, Physical activity, Weight loss
Subjects:
Biomolecules and biochemistry
Food science and nutrition

Cite this dataset as:
Templeman, I., Smith, H., Chowdhury, E., Chen, Y., Carroll, H., Johnson-Bonson, D., Hengist, A., Smith, R., Creighton, J., Clayton, D., Varley, I., Karagounis, L., Wilhelmsen, A., Tsintzas, K., Reeves, S., Walhin, J., Gonzalez, J., Thompson, D., Betts, J., 2021. Dataset for "A randomized controlled trial to isolate the effects of fasting and energy restriction on weight loss and metabolic health in lean adults". Bath: University of Bath Research Data Archive. Available from: https://doi.org/10.15125/BATH-00974.

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Data

Lean Archive IFP.xlsx
application/vnd.openxmlformats-officedocument.spreadsheetml.sheet (9MB)
Creative Commons: Attribution 4.0

Creators

Iain Templeman
University of Bath

Harry Smith
University of Bath

Yung-Chih Chen
University of Bath; National Taiwan Normal University

Harriet Carroll
University of Bath; Lund University

Drusus Johnson-Bonson
University of Bath

Aaron Hengist
University of Bath

Rick Smith
University of Bath

Jade Creighton
University of Bath; Nottingham Trent University

David Clayton
Nottingham Trent University

Ian Varley
Nottingham Trent University

Leonidas Karagounis
Nestlé Health Science; University of Bern

Andrew Wilhelmsen
University of Nottingham

Kostas Tsintzas
University of Nottingham; Yokohama City University

Sue Reeves
University of Roehampton

Dylan Thompson
University of Bath

James Betts
University of Bath

Contributors

University of Bath
Rights Holder

Documentation

Data collection method:

The precise details of and justifications for the experimental design and protocol adopted has been published as follows: Templeman, I., Thompson D., Gonzalez, J.T., Walhin, J.P., Reeves, S., Rogers, P.J., Brunstrom, J.M., Karagounis, L.G., Tsintzas K., Betts, J.A. (2018) Intermittent fasting, energy balance and associated health outcomes in adults: study protocol for a randomised controlled trial. Trials 19 (1): 86. doi:10.1186/s13063-018-2451-8

Additional information:

Any missing data-points are denoted as ‘NA’ in the data.

Methodology link:

Templeman, I., 2015. Impacts of Intermittent Fasting on Energy Balance and Associated Health Outcomes. ClinicalTrials.gov NCT02498002. US National Library of Medicine. Available from: https://clinicaltrials.gov/ct2/show/NCT02498002.

Templeman, I., Thompson, D., Gonzalez, J., Walhin, J.-P., Reeves, S., Rogers, P. J., Brunstrom, J. M., Karagounis, L. G., Tsintzas, K., and Betts, J. A., 2018. Intermittent fasting, energy balance and associated health outcomes in adults: study protocol for a randomised controlled trial. Trials, 19(1). Available from: https://doi.org/10.1186/s13063-018-2451-8.

Documentation Files

README FILE … ARCHIVE IFP.docx
application/vnd.openxmlformats-officedocument.wordprocessingml.document (35kB)
Creative Commons: Attribution 4.0

Funders

Publication details

Publication date: 16 June 2021
by: University of Bath

Version: 1

DOI: https://doi.org/10.15125/BATH-00974

URL for this record: https://researchdata.bath.ac.uk/id/eprint/974

Related papers and books

Templeman, I., Smith, H. A., Chowdhury, E., Chen, Y.-C., Carroll, H., Johnson-Bonson, D., Hengist, A., Smith, R., Creighton, J., Clayton, D., Varley, I., Karagounis, L. G., Wilhelmsen, A., Tsintzas, K., Reeves, S., Walhin, J.-P., Gonzalez, J. T., Thompson, D., and Betts, J. A., 2021. A randomized controlled trial to isolate the effects of fasting and energy restriction on weight loss and metabolic health in lean adults. Science Translational Medicine, 13(598). Available from: https://doi.org/10.1126/scitranslmed.abd8034.

Contact information

Please contact the Research Data Service in the first instance for all matters concerning this item.

Contact person: James Betts

Departments:

Faculty of Humanities & Social Sciences
Health

Research Centres & Institutes
Centre for Nutrition, Exercise and Metabolism (CNEM)